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Recent scientific studies on addiction treatment have focused on pharmacological interventions, behavioral, cognitive, and social interventions, and other non-pharmacotherapies. A Special Collection on Addiction of open access articles, curated by Science Advances editors, focuses on scientific advances in the treatment and recovery mechanisms of addiction related to four widely misused substances: alcohol, nicotine, cocaine, and opioids.

The collection includes comprehensive review articles on these substances authored by leading researchers in the field of addiction, along with research studies that present recent findings. Other studies have explored the use of mindfulness training, LSD, and contingency management in addiction treatment. A recent webinar reviewed the most up-to-date science of addiction, the current arguments for and against addiction’s conceptualization as a disease, and how the latest neuroscientific explanations of substance use disorder (SUD) pathophysiology can inform treatment.